DNA Sequencing with Nanopores

The IBM solution which I may have linked to before, uses holes in silicon chips:

http://www.wired.com/gadgetlab/2009/10/dna-analyzer-on-a-chip/

and here's an approach using an engineered protein called MspA:

http://www.scientificcomputing.com/news-HPC-Jaguar-Supercomputer-Helps-Develop-Affordable-Personal-Genome-Sequencing-022811.aspx?et_cid=1207025&et_rid=41428335